Based on these findings, the researchers estimate that, compared to mammography and ultrasound, screening with MRI will allow detection of 23 more cancers per 1,000 high-risk women screened.

While MRI has been shown to be an effective screening tool for women genetically predisposed to developing breast cancer, there is no evidence to support MRI screening in average-risk women. "Although MRI is a very powerful tool for detecting cancer, it is not perfect," Dr. Lehman cautioned. "There are benign areas of breast tissue that can look suspicious but do not represent breast cancer and yet may lead to a biopsy."

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Article adapted by Medical News Today from original press release.
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Radiology is a monthly scientific journal devoted to clinical radiology and allied sciences. The journal is edited by Anthony V. Proto, M.D., School of Medicine, Virginia Commonwealth University, Richmond, Va. Radiology is owned and published by the Radiological Society of North America, Inc. (http://rsna.org/radiologyjnl)

The Radiological Society of North America (RSNA) is an association of more than 40,000 radiologists, radiation oncologists, medical physicists and related scientists committed to excellence in patient care through education and research. The Society is based in Oak Brook, Ill. (http://rsna.org/)

"Cancer Yield of Mammography, MRI, and Ultrasound in High Risk Women: Prospective Multi-institution Breast Cancer Screening Study." Co-authors of the paper are Thomas Claudine Isaacs, M.D., Mitchell D. Schnall, MD, Ph.D., Etta Pisano, M.D., Susan M. Ascher, M.D., Paul T. Weatherall, M.D., David A. Bluemke, M.D., Ph.D., Deborah J. Bowen, Ph.D., P. Kelly Marcom, M.D., Deborah K. Armstrong, M.D., Susan M. Domchek, M.D., Gail Tomlinson, M.D., Ph.D., Steven Skates, Ph.D., Constantine Gatsonis, Ph.D.

This study was funded by the International Breast MRI Consortium and the Cancer Genetics Network.

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